Since the term odontogenic keratocyst (OKC) has been re-classified several times between cyst and tumor due to a debate over biological behaviors and oncogenic mutation of OKC [1,2]. Although a number of treatment methods have been developed in addition to simple enucleation, surgical approaches are often limited owing to the high recurrence of OKC as well as its locally destructive behavior [3]. While many targeted therapeutics for oncogenic mutation have become widely available recently, the molecular background of OKC and non-invasive therapeutic approaches based on oncogenic mutation have not been widely studied.
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Ιατρική Αλέξανδρος Γ. Σφακιανάκης,Αναπαύσεως 5 Άγιος Νικόλαος 72100 Κρήτη 00302841026182 Medical Articles by Alexandros G.Sfakianakis PhD,Anapafseos 5 Agios Nikolaos 72100 Crete Greece 00306932607174
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Πέμπτη 2 Νοεμβρίου 2017
Frequent oncogenic BRAF V600E mutation in odontogenic keratocyst
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