An unusual case of Takotsubo syndrome with hyperaldosteronism as the potential cause.

An unusual case of Takotsubo syndrome with hyperaldosteronism as the potential cause.

J Clin Endocrinol Metab. 2017 Oct 31;:

Authors: Ou Y, Zhao Z, Tsauo J, Jiang L, Yang Y, Chen M

Abstract
Context: Catecholamine-related factors are currently the most popular explanation for the occurrence of Takotsubo syndrome. The aldosterone-related mechanism, however, has not been proposed.
Case Description: A 45-year old male, presenting with ST-segment elevation myocardial infarction (STEMI), was finally diagnosed with primary aldosteronism, severe hypokalemia, and Takotsubo syndrome. After excluding the known conditions of apical ballooning and the factors of vasospasm, primary aldosteronism is considered as the major contributor to the development of the Takotsubo syndrome. The potential mechanisms are discussed.
Conclusions: The case suggests a possible hyperaldosteronism-induced and vasoconstriction-mediated mechanism in the development of Takotsubo syndrome.

PMID: 29095987 [PubMed - as supplied by publisher]

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