Amitriptyline and topiramate do not demonstrate benefit in pediatric migraine

Powers SW, Coffey CS, Chamberlin LA, Ecklund DJ, Klingner EA, Yankey JW, et al. Trial of Amitriptyline, Topiramate, and Placebo for Pediatric Migraine. N Engl J Med 2017;376:115-24.

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